Pathology Case Study 2

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A 25-year-old woman comes to the clinic for pregnancy testing. She reports that her last menstrual period was 30 days ago. A random urine specimen is collected for testing. The result for this test is reported as negative. The physical examination indicates that the woman is pregnant.

1. What is the possible reason for the false-negative test result?

  • The specific gravity was greater than 1.015
  • The lack of agglutination seen on the test slide was interpreted as a negative test results
  • The test lacks the sensitivity to detect the concentration of hCG present in the specimen.
  • The patient had ingested an excessive amount of aspirin.

2. If conception is estimated to have taken place about 2 weeks before her visit to the clinic and if this is an average pregnancy, what would be the normal average serum hCG concentration at the time of this patient’s visit?

  • 25 m IU/mL
  • 50 m IU/mL
  • 500 m IU/mL
  • 30, 000 m IU/mL

3. If this patient was not pregnant, a reason for a false-positive result could be:

  • A urine specific gravity of less than 1.015
  • Treatment for infertility with an hCG injection
  • Conducting the assay at 1 week of gestation
  • Use of a random urine specimen
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